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Emerging studies showed that in PDAC, KRAS knockdown (10, 13, 55) or the use of selective monoamine antagonist ziprasidone (56, 57) directly targeted and inhibited the expression of GOT1, subsequently disrupting Gln metabolism, affecting NADPH production, elevating ROS levels, and disturbing the redox balance

Abstract Tyrosinase, exquisitely catalyzes the phenolic compounds into brown or black pigment, inhibition is used as a treatment for dermatological or neurodegenerative disorders

doi: 10.1007/BF02633506

Oresajo, T

ZR-75-1 and T47D cells were cultured in DMEM with 10% FBS supplemented with 100 units/mL penicillin and 100 g/mL streptomycin